发明名称 |
NOVEL POLYPEPTIDE SCAFFOLDS AND USE THEREOF |
摘要 |
Novel peptide having a sequence according to SEQ. ID. No.1, SEQ. ID. No. 2 and/or SEQ. ID. No. 3 are disclosed and also polypeptide scaffold consisting of a four helix bundle formed of two dimerized helix-loop-helix motifs, said helix-loop-helix motifs having sequences according to SEQ. ID. No. 1, SEQ. I D. No. 2 and/or SEQ. ID. No. 3 which may comprise a fluorescent probe at the si de chain of Lys15 and a ligand with affinity for a target molecule at the side chain of Lys8 or Lys34. Also disclosed are polypeptide scaffolds for use in biosensing applications with or without the polypeptide scaffold anchored to a solid surface.
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申请公布号 |
CA2480049(A1) |
申请公布日期 |
2003.10.02 |
申请号 |
CA20032480049 |
申请日期 |
2003.03.26 |
申请人 |
BALTZER, LARS |
发明人 |
LUNDSTROEM, INGEMAR;LIEDBERG, BO;BALTZER, LARS;DOLPHIN, GUNNAR |
分类号 |
C07K1/04;C07K1/107;C07K14/00;C07K17/00;(IPC1-7):C07K14/00 |
主分类号 |
C07K1/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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