Sulfonamide derivatives of 3-substituted imidazo¬1,2-D -1,2,4-thiadiazoles and 3-substituted-¬1,2,4 thiadiazolo¬4,5-A benzimidazole as inhibitors of fibrin cross-linking and transglutaminases

摘要

A method of inhibiting the activity of transglutaminases containing a cysteine residue comprising administering to a mammal an effective amount of a sulfonamide derivative of imidazoÄ1,2-dÜ-1,2,4-thiadiazoles sufficient to inhibit the activity.