| 发明名称 |
Non-human transgenic mammals and their use as a disease model |
| 摘要 |
<p>A non-human mammal that carries germline mutations in both the p53 and the Fos genes, methods for producing it and cell lines derived therefrom. <??>The p53/Fos double knockout animal, in particular a mouse, is useful as a rhabdomyosarcoma disease model.</p> |
| 申请公布号 |
EP1348335(A1) |
申请公布日期 |
2003.10.01 |
| 申请号 |
EP20020007129 |
申请日期 |
2002.03.28 |
| 申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
FLEISCHMANN, ALEXANDER;WAGNER, ERWIN;JOCHUM, WOLFRAM;RADOLF, MARTIN |
| 分类号 |
C07K14/47;C07K14/82;C12N15/85;G01N33/50;G01N33/574;(IPC1-7):A01K67/027;C12N5/16;C12N5/10 |
主分类号 |
C07K14/47 |
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