RETINOID ACTIVITY REGULATORS

摘要

Compounds represented by general formula (I), wherein R<1> represents hydrogen or C1-6 alkyl; R<2>, R<3> and R<4> represent hydrogen, C1-6 alkyl, etc.; and X represents a divalent group -C(R<5>)(R<6>)- or -NR<7>- (wherein R<5> represents hydrogen or hydroxy; R<6> represents phenyl or a 5- or 6-membered, saturated or unsaturated nitrogen-containing heterocycle; and R<7> represents hydrogen, C1-12 alkyl optionally having one or more unsaturated bonds, etc.). Because of the effect of regulating the expression of the physiological activities of retinoids such as retinoic acid, these compounds are useful as retinoid activity regulators.