发明名称 |
Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof |
摘要 |
Thiazolo-, oxazolo- and selenazolo[4,5-c]quinolin-4-amines and analogs thereof are described including methods of manufacture and the use of novel intermediates. The compounds are immunomodulators and induce cytokine biosynthesis, including interferon and/or tumor biosynthesis, necrosis factor, and inhibit the T-helper-type 2 immune response. The compounds are further useful in the treatment of viral and neoplastic diseases.
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申请公布号 |
US6627640(B2) |
申请公布日期 |
2003.09.30 |
申请号 |
US20020192416 |
申请日期 |
2002.07.10 |
申请人 |
3M INNOVATIVE PROPERTIES COMPANY |
发明人 |
GERSTER JOHN F.;LINDSTROM KYLE J.;MARSZALEK GREGORY J. |
分类号 |
A61K31/424;A61K31/429;A61K31/4375;A61K31/4738;A61K31/5377;A61P31/12;A61P35/00;A61P37/02;C07D221/00;C07D263/00;C07D277/00;C07D498/04;C07D498/14;C07D513/04;C07D513/14;C07D517/04;(IPC1-7):A61K31/435;A61K31/437;A61K31/436;C07D471/04 |
主分类号 |
A61K31/424 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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