发明名称 Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof
摘要 Thiazolo-, oxazolo- and selenazolo[4,5-c]quinolin-4-amines and analogs thereof are described including methods of manufacture and the use of novel intermediates. The compounds are immunomodulators and induce cytokine biosynthesis, including interferon and/or tumor biosynthesis, necrosis factor, and inhibit the T-helper-type 2 immune response. The compounds are further useful in the treatment of viral and neoplastic diseases.
申请公布号 US6627640(B2) 申请公布日期 2003.09.30
申请号 US20020192416 申请日期 2002.07.10
申请人 3M INNOVATIVE PROPERTIES COMPANY 发明人 GERSTER JOHN F.;LINDSTROM KYLE J.;MARSZALEK GREGORY J.
分类号 A61K31/424;A61K31/429;A61K31/4375;A61K31/4738;A61K31/5377;A61P31/12;A61P35/00;A61P37/02;C07D221/00;C07D263/00;C07D277/00;C07D498/04;C07D498/14;C07D513/04;C07D513/14;C07D517/04;(IPC1-7):A61K31/435;A61K31/437;A61K31/436;C07D471/04 主分类号 A61K31/424
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