C-glycosides and preparation of thereof as antidiabetic agents

摘要

C-glycoside derivatives are disclosed, which are represented by the following formula (I) and its pharmaceutical acceptable salt, and which are useful for the treatment and/or prevention of diabetes and hypoglycemia.wherein: with the provisos thatR1 is H, OH, lower alkyl, O-lower alkyl orR2 is H, -COO-lower alkyl,R5 is -CH2OH, -CH2OCO2-lower alkyl,-CH2OSO3H, -COOH or -COONa;wherein: A is(with the provisos that X is oxygen atom, nitrogen atom or sulfur atomR3 is lower alkyl when m=0, and is lower alkyl, -OH or -O-lower alkyl when m=1, . . . means saturated or unsaturated carbon bond;m is 0 or 1;n is 0, 1 or 2;above mentioned-lower alkyl means C1-C5.)or a pharmaceutical acceptable salt.