| 发明名称 |
NOVEL SYNTHETIC CRYPTOPHYCINES |
| 摘要 |
Novel cryptophycin compounds are disclosed, together with methods of producing cryptophycins by total synthesis and methods for the use of such cryptophycins in pharmaceuticals to inhibit the proliferation of mammalian cells and to treat neoplasia. |
| 申请公布号 |
PL185949(B1) |
申请公布日期 |
2003.09.30 |
| 申请号 |
PL19960322507 |
申请日期 |
1996.03.07 |
| 申请人 |
UNIVERSITY OF HAWAII;WAYNE STATE UNIVERSITY |
发明人 |
MOORE RICHARD E.;TIUS MARCUS A.;BARROW RUSSELL A.;LIANG JIAN;CORBETT THOMAS H.;VALERIOTE FREDERICK A.;HEMSCHEIDT THOMAS K.;GOLAKOTI TRIMURTULU |
| 分类号 |
C07D307/20;A61K31/00;A61K31/34;A61K31/341;A61K31/395;A61P1/00;A61P5/00;A61P11/00;A61P13/00;A61P13/08;A61P15/00;A61P25/14;A61P35/00;A61P35/02;A61P43/00;C07C231/02;C07C237/22;C07D257/02;C07D273/00;C07D273/08;C07D409/04;C07K5/12 |
主分类号 |
C07D307/20 |
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