发明名称 |
ARYLPROPIONIC DERIVATIVE, PROCESS FOR THE PREPARATION AND USE THEREOF AS AN ANALGESIC AGENT |
摘要 |
The invention relates to an arylpropionic derivative which is a tromethamine salt of an arylpropionic acid, namely the tromethamine salt of the (+)-(S)-2-(3-benzoylphenyl)propionic acid, to the process for preparing the same derivative and to the use thereof as an analgesic and anti-inflammatory agent. According to the invention, the derivative has the following general structural formula I: The claimed process for preparing the arylpropionic derivative comprises the reaction of the (+)-(S)-2-(3-benzoylphenyl)propionic acid with the H2NC(CH2OH)3 tromethamine, in equimolar amounts.
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申请公布号 |
RO118712(B1) |
申请公布日期 |
2003.09.30 |
申请号 |
RO19950000865 |
申请日期 |
1993.11.09 |
申请人 |
LABORATORIOS MENARINI SA, BARCELONA |
发明人 |
CARGANICO GERMANO;MAULEN CASELLAS DAVID;GARCIA PEREZ M LUISA |
分类号 |
A61K31/19;A61K31/205;A61P25/04;A61P29/00;C07C5/10;C07C51/41;C07C59/84;C07C215/10;(IPC1-7):C07C59/84 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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