发明名称 ARYLPROPIONIC DERIVATIVE, PROCESS FOR THE PREPARATION AND USE THEREOF AS AN ANALGESIC AGENT
摘要 The invention relates to an arylpropionic derivative which is a tromethamine salt of an arylpropionic acid, namely the tromethamine salt of the (+)-(S)-2-(3-benzoylphenyl)propionic acid, to the process for preparing the same derivative and to the use thereof as an analgesic and anti-inflammatory agent. According to the invention, the derivative has the following general structural formula I: The claimed process for preparing the arylpropionic derivative comprises the reaction of the (+)-(S)-2-(3-benzoylphenyl)propionic acid with the H2NC(CH2OH)3 tromethamine, in equimolar amounts.
申请公布号 RO118712(B1) 申请公布日期 2003.09.30
申请号 RO19950000865 申请日期 1993.11.09
申请人 LABORATORIOS MENARINI SA, BARCELONA 发明人 CARGANICO GERMANO;MAULEN CASELLAS DAVID;GARCIA PEREZ M LUISA
分类号 A61K31/19;A61K31/205;A61P25/04;A61P29/00;C07C5/10;C07C51/41;C07C59/84;C07C215/10;(IPC1-7):C07C59/84 主分类号 A61K31/19
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