Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug

摘要

Granulate, containing an active ingredient, having a solubility in water of 1:>10, in admixture with a water-dispersible cellulose, which is a microcrystalline cellulose and sodium carboxymethyl cellulose, whereby the water-dispersible cellulose constitutes up to 15wt.% relative to the active ingredient.