CDNAS AND PROTEINS BELONGING TO THE BHLH-PAS SUPERFAMILY OF TRANSCRIPTION REGULATORS, AND METHODS OF USE
摘要
The present invention provides isolated nucleic acids and proteins that are new and distinct members of the bHLH-PAS superfamily of transcription regulators. These "MOPs" (members of PAS) are useful in a variety of research, diagnostic and therapeutic applications. Several of the MOPs of the present invention are alpha -class hypoxia-inducible factors. Several other of the MOPs of the invention are involved in circadian signal transduction.
申请公布号
WO9928464(A2)
申请公布日期
1999.06.10
申请号
WO1998US25314
申请日期
1998.11.27
申请人
WISCONSIN ALUMNI RESEARCH FOUNDATION;BRADFIELD, CHRISTOPHER, A.;GU, YI, ZHONG;HOGENESCH, JOHN, B.
发明人
BRADFIELD, CHRISTOPHER, A.;GU, YI, ZHONG;HOGENESCH, JOHN, B.