发明名称 |
PROCEDE DE PREPARATION DU 1,3-PROPANEDIOL PAR UN MICRO-ORGANISME RECOMBINANT EN L'ABSENCE DE COENZYME B12 OU DE L'UN DE SES PRECURSEURS |
摘要 |
The invention concerns a method for preparing 1,3-propanediol from a carbon-containing substance, said method comprising a step which consists in culturing a recombinant micro-organism not producing coenzyme B12 in the absence of coenzyme B12 or one of its precursors. The invention also concerns a nucleic acid coding for a glycerol dehydratase whereof the catalytic activity is independent of the presence of coenzyme B12 or one of its precursors and a nucleic acid coding for a 1,3-propanol dehydrogenase intervening in the synthesis of 1,3-propanediol. The invention further concerns recombinant vectors and host cells comprising said nucleic acids and the polypeptides coded by the latter. |
申请公布号 |
FR2796081(B1) |
申请公布日期 |
2003.09.26 |
申请号 |
FR19990008939 |
申请日期 |
1999.07.09 |
申请人 |
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE INRA |
发明人 |
SARCABAL PATRICIA;CROUX CHRISTIAN;SOUCAILLE PHILIPPE |
分类号 |
C12N1/19;C12N1/21;C12N9/88;C12N15/53;C12N15/60;C12P7/18 |
主分类号 |
C12N1/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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