METHODS FOR PERFORMING FIBRINOGEN ASSAYS USING DRY CHEMICAL REAGENTS CONTAINING ECARIN AND MAGNETIC PARTICLES

摘要

A method of performing a fibrinogen assay is provided using an assay reagent containing ecarin to give an assay that is insensitive to the presence of heparin and insensitive to hematrocrit, while being useful as a point of car e assay in both a dry chemistry and wet chemistry format. A device for performing a fibrinogen assay contains a cover (10), an overlay (20) and a base (30). Cover (10) is a thin glass or polymer sheet transparent to light, having a sample receiving opening (14) and an elongate opening (12) therein. Overlay (20) is a thin glass or polymer sheet having a sample well (22), a reaction chamber (24) and a conduit (26) communicating the reaction chamber (24) with the sample well (22).