| 摘要 |
Assemblies are provided for collecting oral fluid from a mouth of a subject using a hydrophobic/hydrophilic sample collection tip. A sample collection assembly includes a sample collection tip configured for being placed within the mouth, and a conduit in fluid communication with the sample collection tips. The sample collection tip includes a hydrophobic interior and a hydrophilic outer surface. In this manner, the tendency of analytes within the sample to stick to the interior of the sample collection tip is minimized, while allowing wetting of the outer surface of the sample collection tip with the sample to facilitate its collection. The sample collection assembly can further include a hand piece that has a tip on which the sample collection tip is mounted, and through which the conduit can extend. The sample collection tip can have a bore in which the conduit is disposed, e.g., by bonding. The hydrophobic interior of the sample collection tip can be composed of a microporous material, such as high density polyethylene, and the hydrophobic outer surface of the sample collection can include a surfactant. The sample collection tip can have any suitable shape, e.g., hemi-dome shaped.
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