Preparation of amino acids, especially threonine, useful e.g. in animal nutrition, by fermenting Enterobacteriaceae that overexpress the icd gene

摘要

Method for producing L-amino acids (A), especially threonine, by fermenting an (A)-producing organism of the family Enterobacteriaceae in which the intracellular activity of the protein encoded by the icd gene, or related sequences, has been increased, especially by overexpression. Method for producing L-amino acids (A), especially threonine, by fermenting an (A)-producing organism of the family Enterobacteriaceae in which the intracellular activity of the protein encoded by the icd gene, or related sequences, has been increased, especially by overexpression. (A) Accumulates in medium or biomass and is isolated, optionally with retention of some or all of other broth and/or biomass components in the product. An Independent claim is also included for members of the family Enterobacteriaceae, particularly Escherichia, in which intracellular activity of the protein encoded by the adk gene, or related sequences, has been increased.