PROCESS FOR PREPARATION OF trans-4-AMINOCYCLOHEXANE- CARBOXYLIC ACIDS

摘要

A process for the preparation of trans-4-aminocyclo- hexanecarboxylic acid, salts or amino-protected derivatives thereof, or salts of the derivatives, characterized by treating a cis isomer of 4-aminocyclohexanecarboxylic acid or a reactive derivative thereof or a mixture of cis- and trans-isomers of the acid or the reactive derivative with a base selected from the group consisting of sodium hydroxide and potassium alkoxides and, if necessary, protecting the amino group of the obtained compound.