发明名称 |
METHODS OF TREATMENT WITH SELECTIVE EP4 RECEPTOR AGONISTS |
摘要 |
The present invention provides a method of treating hypertension, liver failure, loss of patency of ductus arteriosus, glaucoma or ocular hypertension in a patient, comprising administering to the patient a therapeutically effective amount of a selective EP4 receptor agonist of Formula (I), or a prodrug thereof, a pharmaceutically acceptable salt of the selective EP4 receptor agonist or prodrug or a stereoisomer or diastereomeric mixture of the EP4 receptor agonist, prodrug or salt, wherein the variables X, Z, Q, ---, and R<2> are as defined in the specification.
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申请公布号 |
WO03077910(A1) |
申请公布日期 |
2003.09.25 |
申请号 |
WO2003IB00844 |
申请日期 |
2003.03.06 |
申请人 |
PFIZER PRODUCTS INC.;CAMERON, KIMBERLY, O'KEEFE;LEFKER, BRUCE, ALLEN;KNIGHT, DELVIN, ROSCOE, JR. |
发明人 |
CAMERON, KIMBERLY, O'KEEFE;LEFKER, BRUCE, ALLEN;KNIGHT, DELVIN, ROSCOE, JR. |
分类号 |
C07D403/10;A61K31/4015;A61K31/4025;A61K31/427;A61K31/559;A61P1/16;A61P9/10;A61P9/12;A61P27/06;A61P43/00;C07D207/26;C07D207/27;C07D403/06;C07D403/12;C07D405/06;C07D409/06;C07D409/12;C07D409/14;C07D417/06;C07D417/12;C07D417/14;(IPC1-7):A61K31/401;C07D207/00 |
主分类号 |
C07D403/10 |
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