发明名称 PROCESS FOR THE PREPARATION OF ERGOLINE DERIVATIVES
摘要 The invention provides a process for the preparation of ergoline derivatives of formula (I), the process comprising reacting an ergoline amide of formula (II) with an isocyanate of formula (III) in presence of a metal catalyst and of a phosphorus com- pound. The compounds of formula (I) are useful antiprolactinic and antiparkinson agents.
申请公布号 CA2106371(C) 申请公布日期 2003.09.23
申请号 CA19932106371 申请日期 1993.02.15
申请人 FARMITALIA CARLO ERBA S.R.L. 发明人 CANDIANI, ILARIA;CABRI, WALTER;BEDESCHI, ANGELO;ZARINI, FRANCO
分类号 A61K31/48;A61P5/08;A61P25/16;C07D457/06 主分类号 A61K31/48
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