发明名称 Carboxylic acid amides, medicaments containing these compounds and the use and production thereof.
摘要 Carboxylic acid amides of general formula which inhibit telomerase and are useful for treating tumor diseases such as carcinomas, sarcomas and leukaemias. Exemplary compounds are: (1) trans-3-(naphth-2-yl)-but-2-enoic acid-N-(2-carboxy-phenyl)-amide, and, (2) trans-3-(naphth-2-yl)-but-2-enoic acid-N-(2-carboxy-4,5-dimethoxy-phenyl)-amide.
申请公布号 ZA200200694(B) 申请公布日期 2003.09.23
申请号 ZA20020000694 申请日期 2002.01.25
申请人 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG. 发明人 NORBERT HAUEL;HENNING PRIEPKE;KLAUS DAMM;ANDREAS SCHNAPP
分类号 C07D295/10;A61K31/16;A61K31/165;A61K31/167;A61K31/192;A61K31/194;A61K31/36;A61K31/381;A61K31/41;A61K31/415;A61K31/4164;A61K31/4184;A61K31/439;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/445;A61K31/4453;A61K31/4465;A61K31/47;A61K31/495;A61K31/5375;A61P35/00;A61P43/00;C07C233/46;C07C233/52;C07C233/55;C07C233/63;C07C233/81;C07C235/38;C07C237/30;C07C237/42;C07C237/52;C07C239/20;C07C243/38;C07C255/24;C07C271/20;C07C271/28;C07C275/42;C07C309/51;C07C309/66;C07C311/08;C07C311/13;C07C311/21;C07C311/39;C07C311/46;C07C311/51;C07D207/20;C07D211/16;C07D211/26;C07D213/40;C07D213/53;C07D213/56;C07D213/75;C07D213/79;C07D215/48;C07D215/56;C07D231/12;C07D231/14;C07D231/38;C07D233/26;C07D233/61;C07D233/88;C07D233/90;C07D235/06;C07D235/08;C07D257/04;C07D295/12;C07D295/155;C07D295/192;C07D295/22;C07D307/79;C07D311/06;C07D311/12;C07D317/50;C07D317/68;C07D333/36;C07D333/38;C07D333/40;C07D333/58;C07D333/60;C07D405/04;C07D487/04 主分类号 C07D295/10
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