TANDEM SYNTHETIC HIV-1 PEPTIDES

摘要

Novel synthetic peptides are provided which are candidate vaccines against H IV-1 and which are useful in diagnostic application. The peptides comprise an amino acid sequence of a T-cell epitope of the gag protein of HIV-1, specifically p24E linked directly to a n amino acid sequence of a B-cell epitope of the V3 loop protein of an HIV-1 i solate and containing the sequence GPGR, and/or the gp41 containing the sequence ELKDWA. Multimeric forms of the tandem synthetic pep tides are provided.