| 发明名称 |
Ion channel modulating agents comprising novel benzimidazolone derivatives |
| 摘要 |
The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents.The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
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| 申请公布号 |
US6624186(B2) |
申请公布日期 |
2003.09.23 |
| 申请号 |
US20010854357 |
申请日期 |
2001.05.15 |
| 申请人 |
NEUROSEARCH A/S |
发明人 |
TEUBER LENE;CHRISTOPHERSEN PALLE;STROBAEK DORTE;JENSEN BO SKAANING |
| 分类号 |
C07D235/02;A61K31/4184;A61K31/423;A61K31/428;A61K31/429;A61K31/433;A61K31/437;A61P1/00;A61P1/12;A61P3/10;A61P9/00;A61P9/06;A61P9/10;A61P9/12;A61P11/00;A61P11/06;A61P11/08;A61P13/02;A61P13/10;A61P13/12;A61P15/06;A61P15/08;A61P17/14;A61P21/04;A61P25/00;A61P25/04;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P27/16;A61P35/00;A61P37/06;A61P43/00;C07D235/24;C07D235/26;C07D263/52;C07D263/58;C07D263/60;C07D277/62;C07D277/68;C07D471/04;C07D513/04;(IPC1-7):A61K31/418 |
主分类号 |
C07D235/02 |
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