| 发明名称 |
Cyclopentene derivatives useful as antagonists of the motilin receptor |
| 摘要 |
The compounds of formula I are useful in treating gastrointestinal disorders associated with antagonizing the motilin receptor. The compounds compete with erythromycin and motilin for the motilin receptor. In addition the compounds are antagonists of the contractile smooth muscle response to those ligands.
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| 申请公布号 |
US6624165(B2) |
申请公布日期 |
2003.09.23 |
| 申请号 |
US20020119255 |
申请日期 |
2002.04.09 |
| 申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
CHEN ROBERT H.;XIANG MIN A. |
| 分类号 |
A61P1/06;C07D285/12;C07D285/135;(IPC1-7):C07D417/10;C07D413/10;A61K31/537 |
主分类号 |
A61P1/06 |
| 代理机构 |
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代理人 |
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| 主权项 |
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