发明名称 Compounds useful as reversible inhibitors of cysteine proteases
摘要 Disclosed are novel cathepsin S, K, F, L and B reversible inhibitory compounds of the formula (Ia) and (Ib) where R2, R3, R4, R5, R<6>, R7, R8, Het and X are defined herein. The compounds are useful for treating autoimmune and other diseases. Also disclosed are processes for making such novel compounds.
申请公布号 US6858623(B2) 申请公布日期 2005.02.22
申请号 US20030448698 申请日期 2003.05.29
申请人 BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 发明人 BEKKALI YOUNES;HICKEY EUGENE R.;LIU WEIMIN;PATEL USHA R.;SPERO DENICE M.;SUN SANXING;THOMSON DAVID S.;WARD YANCEY D.;YOUNG ERICK R. R.
分类号 C07D207/16;C07D211/60;C07D211/66;C07D401/12;C07D405/12;C07D413/12;C07D413/14;C07D455/02;C07D487/08;(IPC1-7):A61K31/445;A61K31/404;A61K31/428;A61K31/446;A61K31/452;A61K31/536;A61K31/55;C07D223/06;C07D265/28;C07D263/54;C07D277/62;C07D451/02;C07D239/80 主分类号 C07D207/16
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