| 摘要 |
Diacylhydrazine derivatives of general formula (I)wherein X, Y, Z, R<1>, <2 >and R<3 >are as defined herein, and their physiologically acceptable salts or solvates thereof, are integrin inhibitors and can be used to combat thromboses, myocardial infarcts, coronary cardiac diseases, arteriosclerosis, inflammations, tumors, osteoporosis, infections, and restenosis following angioplasty or during pathological processes that are maintained or propagated by angiogenesis. |
