发明名称 INDOLE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF OSTEOPOROSIS AMONGST OTHER APPLICATIONS
摘要 A compound of formula (1)or a salt thereof, or a solvate thereof,wherein;R1 and R2 each independently represents C1-6alkoxy or halo;R3 and R4 each independently represents hydrogen, C1-6alkoxy, arylC1-6alkoxy, hydroxy, carboxyC1-6alkoxy, hydroxyC1-6alkoxy, dihydroxyC1-6alkoxy, mono- and di-(C1-6alkyl)aminoC1-6alkoxy or aminoC1-6alkoxy, and;R5 represents -NRsRt wherein Rs and Rt each independently represent hydrogen, unsubstituted or substituted C1-6alkyl, or unsubstituted or substituted heterocyclyl, a process for the preparation of such a compound, a pharmaceutical composition containing such a compound and the use of the compound or composition in medicine.
申请公布号 PL352964(A1) 申请公布日期 2003.09.22
申请号 PL20000352964 申请日期 2000.06.16
申请人 GLAXOSMITHKLINE SPA. 发明人 FARINA CARLO;GAGLIARDI STEFANIA;NOVELLA PIETRO A.T.
分类号 A61K31/404;A61K31/4439;A61K31/454;A61K31/496;A61K31/506;A61P1/00;A61P1/04;A61P3/06;A61P9/10;A61P11/00;A61P13/12;A61P17/00;A61P17/06;A61P19/02;A61P19/10;A61P25/28;A61P27/02;A61P29/00;A61P31/04;A61P31/12;A61P31/16;A61P31/18;A61P35/00;A61P35/02;A61P37/06;A61P43/00;C07D209/18;C07D401/12;C07D403/12 主分类号 A61K31/404
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