| 发明名称 |
SULFONYL-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE |
| 摘要 |
This invention comprises the novel compounds of formula (I) wherein n, m, t, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine. |
| 申请公布号 |
AU2003218738(A1) |
申请公布日期 |
2003.09.22 |
| 申请号 |
AU20030218738 |
申请日期 |
2003.03.11 |
| 申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
LEO, JACOBUS, JOZEF BACKX;HANS, LOUIS, JOS DE WINTER;SVEN, FRANCISCUS, ANNA VAN BRANDT;MARC, GUSTAAF, CELINE VERDONCK;LIEVEN MEERPOEL;ISABELLE, NOELLE, CONSTANCE PILATTE;VIRGINIE, SOPHIE PONCELET;ALEXEY, BORISOVICH DYATKIN;KRISTOF VAN EMELEN;JANINE ARTS |
| 分类号 |
C07D249/12;A61K31/40;A61K31/438;A61K31/4427;A61K31/445;A61K31/4545;A61K31/472;A61K31/495;A61K31/496;A61K31/497;A61K31/501;A61K31/506;A61K31/517;A61K31/52;A61K31/53;A61K31/5377;A61K31/55;A61K31/551;A61K45/00;A61P1/04;A61P3/10;A61P5/00;A61P9/00;A61P9/02;A61P9/08;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P13/08;A61P13/10;A61P13/12;A61P15/00;A61P17/00;A61P17/04;A61P17/06;A61P17/10;A61P17/14;A61P17/16;A61P19/02;A61P19/06;A61P21/04;A61P25/00;A61P25/16;A61P25/28;A61P27/02;A61P27/06;A61P29/00;A61P31/18;A61P35/00;A61P35/02;A61P37/02;A61P37/04;A61P37/06;A61P37/08;A61P43/00;C07D;C07D207/09;C07D207/14;C07D207/28;C07D211/26;C07D211/58;C07D213/74;C07D213/78;C07D213/82;C07D215/36;C07D217/02;C07D217/04;C07D233/34;C07D233/64;C07D233/84;C07D233/90;C07D237/24;C07D239/42;C07D239/48;C07D241/04;C07D241/24;C07D241/26;C07D243/08;C07D261/10;C07D295/14;C07D295/155;C07D295/20;C07D295/22;C07D295/26;C07D307/68;C07D307/79;C07D317/58;C07D333/34;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D403/04;C07D403/12;C07D405/12;C07D405/14;C07D409/04;C07D409/12;C07D409/14;C07D413/02;C07D413/04;C07D413/12;C07D471/10;C07D487/08;C07D513/04;C12Q1/48 |
主分类号 |
C07D249/12 |
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