NOVEL ALKALINE PROTEASE VARIANTS AND DETERGENTS AND CLEANSERS CONTAINING THESE NOVEL ALKALINE PROTEASE VARIANTS

摘要

The invention relates to novel alkaline protease variants. These variants have, when enumerating the alkaline protease from Bacillus lentus, variations in amino acid position 61, positions 199 and/or 211 and, optionally, at least one modification that contributes to the stabilization of the molecule, said modification preferably being point mutations in positions 3 and/or 4. Particularly preferred are variants S3T/V4l/G61A/V199l and S3T/V4l/G61A/V199l/L211D of B. lentus alkaline protease. The invention also relates to the possible uses of these enzymes in diverse technical processes and, in particular, to detergents and cleansers containing these novel alkaline protease variants.