| 发明名称 |
METHODS OF INDUCING TERMINAL DIFFERENTIATION |
| 摘要 |
<p>An active ingredient consisting of a crystalline form of suberoylanilide hydroxamic acid (SAHA) having physical characteristics of crystalline SAHA obtainable by a method comprising the step of recrystallizing a crude preparation of SAHA from a mixture of methanol and water.</p> |
| 申请公布号 |
CA2632078(A1) |
申请公布日期 |
2003.09.18 |
| 申请号 |
CA20032632078 |
申请日期 |
2003.03.04 |
| 申请人 |
SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH;MERCK HDAC RESEARCH, LLC |
发明人 |
KELLY, W. KEVIN;MILLER, THOMAS A.;CHIAO, JUDY H.;RICHON, VICTORIA M. |
| 分类号 |
A61K9/48;C07C259/06;A61K31/13;A61K31/16;A61K31/165;A61K31/167;A61K31/19;A61K31/426;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/445;A61K31/4706;A61K31/4709;A61K38/12;A61K47/12;A61K47/38;A61P35/00;A61P43/00;C07C259/04;G01N33/579 |
主分类号 |
A61K9/48 |
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