发明名称 |
BENZOYLBENZOFURANE DERIVATIVES FOR TREATMENT OF CARDIAC ARRHYTHMIA |
摘要 |
The subject invention pertains to novel compounds, and compositions comprising the compounds, for the treatment of cardiac arrhythmias. The subject invention further concerns a method of making the novel compounds. The novel compounds are rapidly metabolized analogs of amiodarone, having the distinct and advantageous characteristic of being metabolized to a less lipophilic compound. The new compounds can have particular utility for treating life-threatening ventricular tachyarrhythmias, especially in patients with congestive heart failure (CHF). The product can also provide effective management for ventricular arrhythmias and supraventricular arrhythmias, including atrial fibrillation and re-entrant tachyarrhythmias involving accessory pathways. |
申请公布号 |
WO0238557(A9) |
申请公布日期 |
2003.09.18 |
申请号 |
WO2001US31305 |
申请日期 |
2001.10.04 |
申请人 |
ARYX THERAPEUTICS;DRUZGALA, PASCAL;MILNER, PETER, G. |
发明人 |
DRUZGALA, PASCAL;MILNER, PETER, G. |
分类号 |
A61K31/343;A61K31/36;A61K31/381;A61K31/405;A61P9/06;C07D209/12;C07D209/18;C07D307/00;C07D307/80;C07D333/54;C07D333/60 |
主分类号 |
A61K31/343 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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