发明名称 COMBINATIONS COMPRISING EPOTHILONE DERIVATIVES AND ALKYLATING AGENTS
摘要 <p>The invention relates to a pharmaceutical combination which comprises (a) an alkylating agent and (b) an epothilone derivative of formula (I) wherein A represents O or NRN, wherein RN is hydrogen or lower alkyl, R is hydrogen or lower alkyl, and Z is O or a bond. Said combination can be useful for the treatment of a proliferative disease, especially a tumor disease.</p>
申请公布号 WO2003075899(P1) 申请公布日期 2003.09.18
申请号 EP2003002364 申请日期 2003.03.07
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