发明名称 INTERFERON BETA-LIKE MOLECULES FOR TREATMENT OF STROKE
摘要 The present invention relates to use of interferon beta-like polypeptides fo r treatment of stroke or transient ischemic attach in a primate, preferably in a human. More particularly, the interferon beta-like polypeptides differs from the amino acid sequence of wild-type human IFNB (SEQ ID NO:2) in that at lea st one glycosylation site, preferably at least one in vivo N-glycosyltaion site has been introduced. Optionally the interferon beta-like polypeptides are PEGylated.
申请公布号 CA2477577(A1) 申请公布日期 2003.09.18
申请号 CA20032477577 申请日期 2003.02.28
申请人 MAXYGEN APS 发明人 SAGER, THOMAS;GLAZER, STEVEN
分类号 C12N15/09;A61K38/21;A61P9/10;C07K14/52;(IPC1-7):A61K38/21 主分类号 C12N15/09
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