摘要 |
The invention provides a human GPR105 which is associated with the genito-urinary diseases, disorders of the nervous system, hematology diseases, cardiovascular diseases, gastro-intestinal diseases, metabolic disorders and cancer. The invention also provides assays for the identification of compounds useful in the treatment or prevention of genito-urinary diseases, disorders of the nervous system, hematology diseases, cardiovascular diseases, gastro-intestinal diseases, metabolic disorders and cancer. The invention also features compounds which bind to and/or activate or inhibit the activity of GPR105 as well as pharmaceutical compositions comprising such compounds. |
申请人 |
BAYER AKTIENGESELLSCHAFT;GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS |
发明人 |
GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS |