发明名称 |
Substituted dithiobisnitrobenzenes and their applications |
摘要 |
The invention concerns substituted dithio-bis-nitrobenzenes (dithio-bis-nitrobenzylamines, dithio-bis-nitrobenzamides or dithio-bis-nitrophenacyls) and their uses as alternative substrates for NAD(P)H-dependent disulphide-reductase enzymes, such as trypanothion reductase and thioredoxine reductase and as a means for screening inhibitors of said enzymes. The invention also concerns an enzymatic test using said substrates and assay kits containing them. Said dithio-bis-nitrobenzenes correspond to general formula (I).
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申请公布号 |
US2003175848(A1) |
申请公布日期 |
2003.09.18 |
申请号 |
US20030348678 |
申请日期 |
2003.01.22 |
申请人 |
INSTITUT PASTEUR DE LILLE |
发明人 |
DAVIOUD-CHARVET ELISABETH;SERGHERAERT CHRISTIAN;BECKER-BRANDENBURG KATJA;SCHIRMER HEINER |
分类号 |
C07C323/22;C07C323/32;C07C323/33;C07C323/62;C07D285/00;C07D295/12;C07D295/18;C07D403/12;C12Q1/26;G01N33/52;G01N33/573;(IPC1-7):C12Q1/26;C0743/02;C0741/02 |
主分类号 |
C07C323/22 |
代理机构 |
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地址 |
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