| 摘要 |
Tablets containing pilsicainide hydrochloride that are orally administered pharmaceuticals superior to injections from the viewpoint of deep regard to direction for use and dosage and ensuring of compliance and that not only ensure easier administration than in the use of capsules but also exhibit desirable tablet hardness and rapid disintegration. In particular, there are provided a process for producing pilsicainide-hydrochloride-containing tablets characterized by containing pilsicainide hydrochloride in a proportion of 5 to 99.5 wt.%, being formed by either effecting compression molding of granules obtained by a dry granulation technique or directly performing compression molding of a powder mixture, having a tablet hardness of 2.5 kg or more free from aging drop, and exhibiting rapid disintegration property; and tablets containing pilsicainide hydrochloride, produced by the process.
|
