发明名称 |
N-hydroxyformamidine derivatives |
摘要 |
An N-hydroxyformamidine compound of the following formula or a pharmaceutically acceptable salt thereof: wherein R<SUP>1</SUP>, A and R are as defined herein. The compounds inhibit 20-HETE-producing enzymes, 20-HETE being involved in the effects of causing microvascular constriction or dilation in major organs (e.g., kidneys, cerebral blood vessels) or of inducing cell proliferation.
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申请公布号 |
US7288566(B2) |
申请公布日期 |
2007.10.30 |
申请号 |
US20050527716 |
申请日期 |
2005.03.11 |
申请人 |
TAISHO PHARMACEUTICAL CO., LTD. |
发明人 |
SATO MASAKAZU;KAKINUMA HIROYUKI;AMADA HIDEAKI |
分类号 |
C07C249/04;A61K31/155;A61K31/40;A61P9/00;A61P13/12;A61P43/00;C07C251/34;C07C259/14;C07D207/06;C07D295/135;C07D319/06 |
主分类号 |
C07C249/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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