METHODS FOR REDUCING BODY FAT AND INCREASING A LEAN BODY MASS BY REDUCING STEAROYL-COA DESATURASE 1 ACTIVITY
摘要
It is disclosed here that inhibiting the activity of the enzyme stearoyl-CoA desaturase (SCD1) in an animal causes the animal to have less body fat and greater lean body mass. The lower of SCD1 activity leval can be accomplished by inhibiting activity of the enzyme or lowering levels of active enzyme in the subject.
申请公布号
WO03075925(A1)
申请公布日期
2003.09.18
申请号
WO2003US05966
申请日期
2003.02.26
申请人
WISCONSIN ALUMNI RESEARCH FOUNDATION
发明人
NTAMBI, JAMES, M.;ATTIE, ALAN, D.;MIYAZAKI, MAKOTO;STOEHR, JONATHAN, P.