发明名称 |
Novel mutant allergens |
摘要 |
Novel recombinant allergens with multiple mutations and reduced IgE binding affinity are disclosed. The allergens are non-naturally occurring mutants of naturally-occurring allergens. The overall alpha-carbon backbone tertiary structure is essentially preserved. Also disclosed is a method for preparing such recombinant allergens as well as uses thereof.
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申请公布号 |
US2003175312(A1) |
申请公布日期 |
2003.09.18 |
申请号 |
US20010001245 |
申请日期 |
2001.11.15 |
申请人 |
ALK-ABELLO A/S |
发明人 |
HOLM JENS;IPSEN HANS HENRIK;LARSEN JORGEN NEDERGAARD;SPANGFORT MICHAEL DHO |
分类号 |
A61K39/00;C07K14/415;C07K14/435;C07K16/16;(IPC1-7):A61K39/35;A61K39/36 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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