| 摘要 |
Compositions and methods for the therapy and diagnosis of cancer, particularly Her-2/neu-associated cancers, are disclosed. Illustrative compositions comprise one or more Her-2/neu polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of Her-2/neu-associated malignancies. |
| 申请人 |
CORIXA CORPORATION;HAND-ZIMMERMANN, SUSAN;CHEEVER, MARTIN, A.;FOY, TERESA, M.;LODES, MICHAEL, J.;KALOS, MICHAEL, D.;MCNEILL, PATRICIA, D.;VEDVICK, THOMAS, S. |
发明人 |
HAND-ZIMMERMANN, SUSAN;CHEEVER, MARTIN, A.;FOY, TERESA, M.;LODES, MICHAEL, J.;KALOS, MICHAEL, D.;MCNEILL, PATRICIA, D.;VEDVICK, THOMAS, S. |
