摘要 |
<p>The production process of the present invention comprises a step of allowing a carboxylic acid derivative represented by the formula (1): <CHEM> wherein ring Z is a monocyclic or polycyclic non-aromatic or aromatic ring, and R<1> is a halogen atom or a group represented by the formula (2): -OR wherein R is a hydrogen atom or a hydrocarbon group, to react with an organometallic compound represented by the formula (3) : R<2>-M wherein R<2> is a hydrocarbon group, and M is a metallic atom which may have a ligand, or the formula (4): -MgY wherein Y is a halogen atom, and a carboxylic acid halide represented by the formula (5): <CHEM> wherein R<3> is a hydrocarbon group or a heterocyclic group, and X is a halogen atom, to yield the tertiary alcohol ester represented by the formula (6): <CHEM> wherein Z, R<2> and R<3> have the same meanings as defined above.. According to the present invention, a tertiary alcohol compound having a tertiary carbon combined with a ring group can be easily and efficiently produced from carboxylic acid derivative which is comparatively cheap and readily available.</p> |