| 发明名称 |
Inhibitors of bone reabsorption and antagonists of vitronectin receptors |
| 摘要 |
The present invention relates to 5-membered ring heterocycles of the formula I,in which E, F, G, W, Y and Z have the meaning given in the patent claims, to their preparation and to their use as medicaments.The novel compounds are used as vitronectin receptor antagonists and as inhibitors of bone reabsorption.
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| 申请公布号 |
US6620820(B2) |
申请公布日期 |
2003.09.16 |
| 申请号 |
US20020078398 |
申请日期 |
2002.02.21 |
| 申请人 |
HOECHST AKTIENGESELLSCHAFT;GENENTECH, INC. |
发明人 |
WEHNER VOLKMAR;KNOLLE JOCHEN;STILZ HANS ULRICH;CARNIATO DENIS;GOURVEST JEAN-FRANCOIS;GADEK TOM;MCDOWELL ROBERT |
| 分类号 |
C07D233/24;A61K31/415;A61K31/4166;A61K31/435;A61K31/505;A61P3/08;A61P9/00;A61P9/08;A61P9/10;A61P13/02;A61P15/00;A61P27/02;A61P29/00;A61P35/00;A61P43/00;C07D233/76;C07D233/96;C07D403/12;C07D405/14;C07D471/04;C07D471/10;(IPC1-7):A61K31/474 |
主分类号 |
C07D233/24 |
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