| 发明名称 |
ANABASEINE DERIVATIVES USEFUL IN THE TREATMENT OF DEGENERATIVE DISEASES OF THE NERVOUS SYSTEM |
| 摘要 |
This invention relates to novel anabaseine-related compounds that are useful in ameilirating memory loss caused by certain degenerative neural diseases such as Alzheimer's and Parkinson's diseases, which apparently involve decreased function of cerebral cortical nicotinic receptors. An exemplary active compound is 3-(2,4dimethoxy)benzylidene anabaseine. Others have the general formula: (see formula I)
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| 申请公布号 |
CA2142610(C) |
申请公布日期 |
2003.09.16 |
| 申请号 |
CA19932142610 |
申请日期 |
1993.08.31 |
| 申请人 |
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. |
发明人 |
KEM, WILLIAM R.;ZOLTEWICZ, JOHN A.;MEYER, EDWIN M.;PROKAI-TATRAI, KATALIN |
| 分类号 |
C07D211/10;A61K31/4427;A61K31/444;A61K31/445;A61K31/4458;A61K31/451;A61K31/4545;A61P25/00;A61P25/28;C07D211/26;C07D211/70;C07D211/82;C07D401/04;C07D405/14;(IPC1-7):C07D401/04;A61K31/44 |
主分类号 |
C07D211/10 |
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