METALLOPROTEASE INHIBITORS CONTAINING A HETEROCYCLIC MOIETY
摘要
The present invention relates generally to pharmaceutical agents containing a heterocyclic moiety, and in particular, to heterocyclic metalloprotease inhibiting compounds. More particularly, the present invention provides a new class of heterocyclic MMP-13 inhibiting compounds with a benzoxazinone moiety, that exhibit an increased potency and selectivity in relation to currently known MMP-13 inhibitors.
申请公布号
WO2008109180(A2)
申请公布日期
2008.09.12
申请号
WO2008US03195
申请日期
2008.03.07
申请人
ALANTOS PHARMACEUTICALS HOLDING, INC.
发明人
GEGE, CHRISTIAN;BLUHM, HARALD;HOCHGUERTEL, MATTHIAS;SCHNEIDER, MATTHIAS;CHEVRIER, CARINE;TAVERAS, ARTHUR