发明名称 Separation of polypeptide monomers
摘要 A method is disclosed for separating a polypeptide monomer from a mixture comprising dimers and/or multimers. The method comprises applying the mixture to either a cation-exchange chromatography resin or an anion-exchange chromatography resin and eluting the mixture at a gradient of about 0-1 M of an elution salt, wherein the monomer is separated from the dimers and/or multimers present in the mixture.
申请公布号 US6620918(B2) 申请公布日期 2003.09.16
申请号 US19990320100 申请日期 1999.05.26
申请人 GENENTECH, INC. 发明人 ANSALDI DEBORAH ANN;LESTER PHILIP
分类号 G01N30/26;B01J20/285;C07K1/18;C07K14/765;C07K16/06;C07K16/42;G01N30/34;G01N30/74;G01N30/88;(IPC1-7):C07K1/18;C07K1/20;C07K1/22;C07K1/14 主分类号 G01N30/26
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