| 摘要 |
The invention concerns methods for the treatment of one or several states conditioned by ??38-kinase activity, consisting in the incorporation into the body of patient requiring such treatment of at least one compound of the formula (??) or pharmaceutically acceptable salt thereof, prodrugs or solvate, where R3 denotes hydrogen, methyl, perfluormethyl, methoxy, halogen, cyano or NH2, better - methyl, and X, R1-R6 and Z have values according to this description. In the optimal variant of the group ZR4R5, taken together, form N??-substituted aryl.
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