摘要 |
<p>A method for providing information for deciding on a therapeutic strategy for a patient, comprising the step of assessing the activity of a transcription factor in a cell or cells from the patient, comprising the steps of (1) exposing the cell or cells to a recombinant viral vector comprising a reporter gene which comprises a promoter under the control of the transcription factor (transcription factor-dependent promoter); and (2) assessing the expression of the reporter gene in the said cell or cells. A method for characterising the hormone dependency of a primary cancer cell or cells, comprising the steps of (1) exposing the cell or cells to a recombinant viral vector comprising a reporter gene which comprises a hormone-dependent promoter; and (2) assessing the expression of the reporter gene in the said cell or cells.</p> |