LIQUID MATRIX UNDERGOING PHASE TRANSFER IN VIVO AND LIQUID ORAL PREPARATIONS

摘要

It is intended to provide a liquid matrix for medicinal use in which a drug can be easily solubilized, dispersed or suspended and which can be easily swallowed because of being a liquid, has favorable working properties in sterilization and so on and a high stability, also exhibits an effect of masking bitterness, and gels in vivo so as to control the release speed, and liquid oral preparations using the same. Namely, a liquid matrix which is a liquid auxiliary facilitating the swallowing of a drug, characterized by containing a water-soluble polymer gelling under acidic conditions and the break stress of the gel being about 3.0x103 N/m2 or more. Liquid oral preparations having favorable slow release properties even though being a liquid.