NON-PEPTIDE IMMUNOLOGIC TRACER PRECURSORS COMPRISING A TYROSYL-(X)N OR LYSINE-(X)N TYROSINE MOTIF, METHOD FOR PREPARING SAME AND USES THEREOF

摘要

The invention concerns an immunologic tracer characterized in that it comprises a non-peptide hapten coupled with a TYR-(X)n-LYS or LYS-(X)n-TYR motif, wherein X is selected among a single bond, an amino acid, except for Lysine, Glutamine, Asparagine or Tyrosine, a succinyl group, a citrate group, a hydroxymethyl-(CH(OH)- group, a methylene group: -CH2-, an oxygen atom, a sulphur atom, an oxyethylene-CH2-O- group, or a methylamine -CHNH- group, and n is an integer ranging between 1 and 20, preferably between 1 and 10, more preferably between 1 and 2. The invention also concerns methods for preparing said precursors, the use thereof for preparing immunologic markers useful in competitive immunologic assays.