HALOGENATED- alpha , beta -UNSATURATED- beta -(SUBSTITUTED-AMINO) CARBOXYLATE ESTERS

摘要

A process for preparing a halogenated aliphatic- alpha , beta -unsaturated- beta -nucleophile-functionalized carboxylate ester having the formula: R<1>-C(-Nu)=CH-COOR<8> by reacting a nucleophile with a halogenated aliphatic- alpha , beta -unsaturated- beta halocarboxylate ester having the formula: R<1>-CX<1>=CH-COOR<8>, wherein R<1> is selected from the group consisting of straight chain and branched halogenated C1-C12 aliphatic groups; Nu is a nucleophile moiety different from X<1>; X<1> is F, Cl or Br; and R<8> is selected from the group consisting of straight chain and branched C1-C6 alkyl groups. Halogenated aliphatic- alpha , beta -unsaturated- beta -nucleophile-functionalized carboxylate esters, halogenated aliphatic- alpha , beta -unsaturated- beta -halocarboxylate esters, and intermediate compounds and processes in the preparation thereof are also disclosed.