| 摘要 |
<p>According to the invention there is provided a method of treatment of a finely divided powdered medicament having a particle size smaller than 10 um and poor flowing properties to form, in a controlled manner, agglomerates or pellets which are free flowing and which are capable of breaking down to provide the finely divided medicament, comprising the steps of agglomeration of the finely divided powdered medicament by feeding the material to a screw feeder, letting the material pass through the screw feeder thereby obtaining agglomerates, spheronising the resulting agglomerates in order to obtain agglomerates which are more spherical, more dense and more compact than the agglomerates obtained from the agglomeration process in the screw feeder, and sizing the agglomerates to obtain a uniform size of the final product. According to the invention there is also provided an apparatus for carrying out the method.</p> |
