发明名称 |
Polymeric micelle containing cisplatin enclosed therein and use thereof |
摘要 |
A complex comprising cisplatin and a poly(ethylene glycol)/poly(glutamic acid) block copolymer, wherein the cisplatin is enclosed in the copolymer through ligand displacement in which a carboxyl anion of the copolymer is replaced with a chlorine ion of the cisplatin. This complex can give a medicine reduced in toxicity and usable by a new method of administration.
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申请公布号 |
US2003170201(A1) |
申请公布日期 |
2003.09.11 |
申请号 |
US20030381339 |
申请日期 |
2003.05.05 |
申请人 |
KATAOKA KAZUNORI;NISHIYAMA NOBUHIRO;YOKOYAMA MASAYUKI;OKANO TERUO |
发明人 |
KATAOKA KAZUNORI;NISHIYAMA NOBUHIRO;YOKOYAMA MASAYUKI;OKANO TERUO |
分类号 |
A61K9/107;A61K9/51;A61K33/24;A61K38/00;A61K47/48;C08G69/40;C08G69/44;(IPC1-7):A61K31/74;A61K38/16 |
主分类号 |
A61K9/107 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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