PHARMACEUTICAL COMPOSITIONS FOR PREVENTION OR TREATMENT OF NEUROINFLAMMATORY DISEASES COMPRISING EXTRACTS OF DENDROPANAX MORBIFERA

摘要

The present invention relates to a composition for treating or preventing neuroinflammatory diseases including Dendropanax Morbifera extract, and more particularly, to a composition which includes, as an active ingredient, a Dendropanax Morbifera extract and is capable of effectively preventing or treating neuroinflammatory diseases through reduction in production of toxic factors or inflammatory cytokine generated in microglia. The Dendropanax Morbifera extract of the present invention does not show toxicity on cells and effectively inhibits the activity of microglia associated with neuroinflammation, thereby being usefully applied as an agent for preventing or treating neuroinflammatory diseases such as Alzheimer′s disease, Parkinson′s disease, Huntington disease, Lou Gehrig′s disease, Creutzfeldt-Jakob′s disease, and multiple sclerosis or a health functional food for preventing or alleviating neuroinflammatory diseases.